1. WildCard Records
To manage subdomains in YunoHost/Coolify/Dokploy or any other container management software with integrated reverse proxy you can send all subdomain request all to the same IP address. This allows you adding each one to Cloudflare, you can create a wildcard DNS record. This means adding a wildcard A record (e.g., *.yourdomain.com) that points to your server's IP address, allowing any subdomain to resolve without additional configuration.
Explanation by cloudflare about wildcards
https://developers.cloudflare.com/dns/manage-dns-records/reference/wildcard-dns-records/